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First Disabled Astronaut to go to the International Space Station

A white man, John McFall who is the first disabled man to go into space, he has short brown hair, wears a blue polo shirt and red shorts, he has a lower limb difference and has a prothetic leg and is smiling whilst stood in an aircraft hangar with airplanes behind him

Written by

Sam Cleasby

Published on

February 18, 2025

John McFall will become the first person with a physical disability to take part in a mission to the International Space Station (ISS). John has a lower limb difference after losing his leg in a motorbike accident when he was 19.

He is a Paralympian, surgeon and Trauma and Orthopaedic Specialist Registrar and has been chosen to undertake a long-duration mission after being selected to take part in ESA’s Fly! Feasibility study in 2022, to look at the challenges of getting an astronaut with a disability to the ISS.

“A really important milestone in the history of human spaceflight”

The study concluded in late 2024 and successfully demonstrated it is technically feasible to fly someone with a physical disability, like John’s, on a six-month mission to the ISS as a fully integrated crew member.  The end of the feasibility study marks the start of the next phase: Fly! Mission Ready. 

Image of the international space station and the earth below it

John said:

It’s great that we can say after a huge amount of work in the last 18 months that we have demonstrated that it’s technically possible for someone with a disability like mine to fly on a long duration mission. And now we’re progressing to the next phase and what we want to do is realise that opportunity to fly, so moving forward, we’re moving into the Mission Ready phase.

The Mission Ready phase is an important step in moving forward to realise a potential flight opportunity. This phase will include looking at hardware certification and moving further down that process. We’re going to be looking at what potential science could be conducted on the International Space Station should I get the opportunity to fly and importantly we’re looking towards medical certification for me to fly on a long duration mission.

One of the roles of an astronaut is to do important science in microgravity whilst working in space and it’s really my hope that if I get the chance to fly we realise what we do in space, the things we learn, the problems we solve, the technology that we develop has a trickle-down effect and benefits people here on earth in wider society.

This progression to the Mission Ready phase is a really important milestone in the history of human spaceflight.

John McFall

Ground-breaking work

Liz Johns, Interim Head of Space Exploration at the UK Space Agency, said:

It is fantastic to see that John and the team at ESA have proved it is technically possible for someone with a physical disability like his to live and work on the International Space Station.   

This is ground-breaking work that no other space agency has done before. Now we are looking forward to supporting John during the next phase: Fly! Mission Ready. This is an essential step towards the first long-term mission for an astronaut with a physical disability.

Liz Johns

What an exciting time for disabled people, We’re sure you will join all of us at Purpl in cheering John on in his space mission! You can find out more about John McFall and the European Space Agency here.


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